Linaclotide,851199-59-2
Product introduction

Product Name:Linaclotide

Synonyms:linaclotide (usan)

CAS No.:851199-59-2

Catalog No.:GT-B019

Sequence:H–Cys1–Cys2–Glu3–Tyr4–Cys5–Cys6–Asn7–Pro8–Ala9–Cys10–Thr11–Gly12–Cys13–Tyr14–OHDisulfide bond(Cys1 and Cys6, Cys2 and Cys10,Cys5 and Cys13)

Molecular Formula:C59H79N15O21S6

Molecular Weight:1526.74

Liralotide chemical formula.png

Key Specification:

Appearance: White powder
Purity(HPLC): ≥98.0%
Single Impurity(HPLC): ≤1.0%
Acetate Content(HPLC): 5.0%~12.0%
Water Content (Karl Fischer): ≤10.0%

Package: 500mg,1g, 5g, 10g, 20g, 50g, 100g, 200g, 500g


Description:

Linaclotide is a guanylate cyclase C agonist composed of 14-amino acid peptides in the shape of a white to off-white amorphous powder.Slightly soluble in water and sodium chloride aqueous solution (0. 9%).After the los peptide oral enter human body through in intestinal type guanylate cyclase C acid receptor (GC - C), make the intracellular and extracellular cGMP (cGMP) levels, stimulate the intestinal fluid secretion, accelerate the migration of gastrointestinal tract, thus increase defecation frequency, because of its unique mechanism of action, is expected to become a kind of not only can treat constipation, also can treat abdominal distension, abdominal pain and other clinical symptoms of drug treatment.


Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use. 

Product Name:LinaclotideLinaclotide Packaging figure


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