Tirzepatide manufacturer/2023788-19-2/Peptide customization

Description

Tirzepatide is a dual agonist of GLP-1 and GIP receptors. GLP-1 and GIP are two endogenous hormones involved in the body's blood glucose regulation mechanisms. Tirzepatide can activate GLP-1 and GIP receptors, thereby reducing hunger, decreasing food intake, and increasing energy expenditure. Some studies suggest that Tirzepatide may increase the risk of thyroid cancer and is not suitable for patients with medullary thyroid carcinoma.

Specifications

Apperance: White to off-white powder

Purity(HPLC): ≥98.0%

Single Impurity: ≤2.0%

Acetate Content(HPLC): 5.0%～12.0%

Water Content (Karl Fischer): ≤10.0%

Peptide Content: ≥80.0%

Packing and Shipping: Low temperature, vacuum packing, accurate to mg as required.

FAQ：

Which end is best for my research?

By default, the peptide ends with an N-terminal free amino group and a C-terminal free carboxyl group. The peptide sequence often represents the sequence of the mother protein. In order to be closer to the mother protein, the end of the peptide often needs to be closed, that is, n-terminal acetylation and C-terminal amidation. This modification avoids the introduction of excess charge, and also makes it more able to prevent exonucliase action, so that the peptide is more stable.

Which modified labeled polypeptides can be synthesized in Chinese peptide?

Our company provides a variety of modified peptide labeling, such as acetylation, biotin labeling, phosphorylation modification, fluorescence modification, can also be customized according to your special needs.

Are polypeptides harmful to humans?

Peptides, which are naturally present in the human body, are generally safe for use. However, some peptides may have specific pharmacological activities, and it is advisable to consult with a doctor or a professional before using them.

How is the solubility of peptides? 

The solubility of peptides is influenced by various factors, including amino acid sequence, charge, hydrophilicity and hydrophobicity, etc. When dissolving peptides, it is recommended to conduct a small-scale solubility test first, and after confirming complete dissolution, proceed with dilution. Go top bio provides solubility testing services.

How to choose the salt form of peptides?

The choice of the salt form of peptides needs to consider various factors, including the peptide sequence, stability, solubility, biotoxicity, and specific experimental requirements. By default, peptides are generally delivered as trifluoroacetic acid (TFA) salts; in addition, peptides can also exist in forms such as acetate, ammonium, and sodium salts.