Tirzepatide supplier/2023788-19-2/Peptide raw materials

Description

Tirzepatide is a medication developed by Eli Lilly for the treatment of type 2 diabetes and obesity. It is a dual agonist of the GIP and GLP-1 receptors. Tirzepatide activates GLP-1 receptors to reduce feelings of hunger, thereby decreasing food intake and caloric consumption; at the same time, it can also activate GIP receptors to reduce food intake and caloric consumption while increasing energy expenditure.

Specifications

Apperance: White to off-white powder

Purity(HPLC): ≥98.0%

Single Impurity: ≤2.0%

Acetate Content(HPLC): 5.0%～12.0%

Water Content (Karl Fischer): ≤10.0%

Peptide Content: ≥80.0%

Packing and Shipping: Low temperature, vacuum packing, accurate to mg as required.

FAQ：

What is Net Peptide Content?
It is important to understand the difference between net peptide content and total peptide weight (gross weight). In general, peptide lyophilized powder samples contain not only peptides, but also other substances such as water, solvents absorbed by peptides, counterions, and salts. The total peptide weight (gross weight) refers to the weight of all these mixtures. The net peptide content is relative to the non-peptide substances, balanced ions and water, and after removing these, the remaining is the net peptide content. The net peptide content can be determined by nitrogen analysis or amino acid composition analysis, usually accounting for 50-80% of the total peptide weight. Net peptide content is different from peptide purity, which refers to the percentage of peptide of interest in a sample.

What are the applications of peptide libraries?
Peptide libraries are an efficient tool for many studies, including GPCR ligand screening, protein-protein interaction studies, functional proteomics, nucleotide binding, screening of enzymatically acting substrates and inhibitors, antigen and epitope screening, signaling molecule search, and other important processes of drug screening.

What do I need to pay attention to when introducing fluorescent modifications into peptides?
It is recommended to add a linker between the peptide molecule and the fluorescent modification, which can reduce the effect of the fluorescent modification on the peptide folding and binding to the receptor. However, if the purpose of the fluorescence modification is to quantify the fluorescence migration between different structures, the introduction of a linker is not recommended.

How to choose the salt form of peptides?

The choice of the salt form of peptides needs to consider various factors, including the peptide sequence, stability, solubility, biotoxicity, and specific experimental requirements. By default, peptides are generally delivered as trifluoroacetic acid (TFA) salts; in addition, peptides can also exist in forms such as acetate, ammonium, and sodium salts.

How To Order?

1. Contact us directly by phone or email: +86-13735575465, sales1@gotopbio.com.

2. Order online. Please fill out the order online form.

3. Provide peptide name, CAS No. or sequence, purity and modification if required, quantity, etc. we will provide a quotation within 2 hours.

4. Order conformation by duly signed sales contract and NDA(non disclosure agreement) or confidential agreement.

5. We will continuously update the order progress in time.

6. Peptide delivery by DHL, Fedex or others, and HPLC, MS, COA will be provided along with the cargo.

7. Refund policy will be followed if any discrepancy of our quality or service.

8. After-sale service: If our clients have any questions about our peptide during experiment, please feel free to contact us and we will respond to it in a short time.

All products of the company are only used for scientific research purpose, it’s prohibited to be directly used by any individuals on human body.