Ovagen supplier/Peptide purification/Custom peptide

Ovagen is a peptide bioregulator developed to protect and restore liver cells. It's designed to correct pathological changes in the liver. Specifically, it's a tripeptide composed of glutamic acid (Glu), aspartic acid (Asp), and leucine (Leu).

Specifications

Apperance: White to off-white powder

Purity(HPLC): ≥98.0%

Single Impurity: ≤2.0%

Acetate Content(HPLC): 5.0%～12.0%

Water Content (Karl Fischer): ≤10.0%

Peptide Content: ≥80.0%

Packing and Shipping: Low temperature, vacuum packing, accurate to mg as required.

FAQ：

Which end is best for my research?

By default, the peptide ends with an N-terminal free amino group and a C-terminal free carboxyl group. The peptide sequence often represents the sequence of the mother protein. In order to be closer to the mother protein, the end of the peptide often needs to be closed, that is, n-terminal acetylation and C-terminal amidation. This modification avoids the introduction of excess charge, and also makes it more able to prevent exonucliase action, so that the peptide is more stable.

What are the applications of peptide libraries?
Peptide libraries are an efficient tool for many studies, including GPCR ligand screening, protein-protein interaction studies, functional proteomics, nucleotide binding, screening of enzymatically acting substrates and inhibitors, antigen and epitope screening, signaling molecule search, and other important processes of drug screening.

Are polypeptides harmful to humans?

Peptides, which are naturally present in the human body, are generally safe for use. However, some peptides may have specific pharmacological activities, and it is advisable to consult with a doctor or a professional before using them.

What do I need to look for when designing phosphorylated peptides?

When designing phosphorylation modifications, the phosphorylation modifications should not be more than 10 amino acids away from the N-terminus to avoid a decrease in coupling efficiency.

What is Net Peptide Content?
It is important to understand the difference between net peptide content and total peptide weight (gross weight). In general, peptide lyophilized powder samples contain not only peptides, but also other substances such as water, solvents absorbed by peptides, counterions, and salts. The total peptide weight (gross weight) refers to the weight of all these mixtures. The net peptide content is relative to the non-peptide substances, balanced ions and water, and after removing these, the remaining is the net peptide content. The net peptide content can be determined by nitrogen analysis or amino acid composition analysis, usually accounting for 50-80% of the total peptide weight. Net peptide content is different from peptide purity, which refers to the percentage of peptide of interest in a sample.