ZP8396(petrelintide) supplier/2766385-23-1/Chinese supplier

Description

ZP8396(petrelintide) is an amylin analogue that has shown the potential for weight loss. Petrelintide can be used for diabetes research.

Specifications

Apperance: White to off-white powder

Purity(HPLC): ≥98.0%

Single Impurity: ≤2.0%

Acetate Content(HPLC): 5.0%～12.0%

Water Content (Karl Fischer): ≤10.0%

Peptide Content: ≥80.0%

Packing and Shipping: Low temperature, vacuum packing, accurate to mg as required.

FAQ：

Which end is best for my research?

By default, the peptide ends with an N-terminal free amino group and a C-terminal free carboxyl group. The peptide sequence often represents the sequence of the mother protein. In order to be closer to the mother protein, the end of the peptide often needs to be closed, that is, n-terminal acetylation and C-terminal amidation. This modification avoids the introduction of excess charge, and also makes it more able to prevent exonucliase action, so that the peptide is more stable.

What is net weight? What is peptide content?

After lyophilized peptide is generally fluffy and fluff-like, it may still contain trace amounts of water, adsorbed solvents and salts due to the characteristics of peptide itself. This does not mean that the purity of the peptide is not enough, but that the actual content of the peptide is reduced by 10% to 30%. The net weight of the peptide is the actual weight of the peptide minus the water and protonated ions. In order to ensure the concentration of peptide, the non-peptide substances need to be removed from the crude peptide.

How pure can the peptide be?

Our company can provide different purity levels for customers to choose from, from crude to > 99.9% purity. According to customer needs we can provide purity > 99.9% ultra-pure polypeptide.

What is the direction of synthesis of peptides?
Peptide synthesis is from the C-terminus to the N-terminus of the polypeptide.

What are the best preservation conditions? How stable is the peptide?

After lyophilized, polypeptide can form fluff or flocculant powder, which can avoid premature degradation of polypeptide. Recommended storage conditions: a. -20℃ storage or dry environment b. Try to avoid repeated freeze-thaw c. Try to avoid storage in solution state (freeze-dried powder can be stored in separate packages for convenience of use) d. If it must be stored in solution, it is recommended to dissolve the peptides in sterile water under weakly acidic conditions and store at -20℃.

Which modified labeled polypeptides can be synthesized in Chinese peptide?

Our company provides a variety of modified peptide labeling, such as acetylation, biotin labeling, phosphorylation modification, fluorescence modification, can also be customized according to your special needs.

Why should peptides be modified by N-terminal acetylation and C-terminal amidation?
Such modifications can give peptide sequences properties that are native to proteins.