Antibacterial tridecapeptide-1 refers to a polypeptide composed of 13 amino acids with antimicrobial and other bioactive functions. Here is a brief introduction to it:
Basic information
Antibacterial tridecapeptide-1 is a short-chain polypeptide with 13 amino acids, which can be synthesized artificially or obtained through bionic engineering technology.
Mechanism of action
Damaging the cell membrane: It may adhere to the cell membrane of bacteria, alter its structure, increase the permeability of the membrane, and thus cause the leakage of substances within the cell, ultimately leading to the death of the bacteria.
Interfere with cell metabolism: Upon entering bacterial cells, it affects crucial metabolic processes such as DNA synthesis and protein synthesis, thereby inhibiting bacterial reproduction.
Main functions
Antibacterial anti-inflammatory: It has an inhibitory effect on Gram-positive bacteria, Gram-negative bacteria, fungi and yeast, and has a wide range of antibacterial effects. For example, it can effectively inhibit Staphylococcus aureus, Propionibacterium acne, Pseudomonas aeruginosa, etc., so it can be used to treat diseases related to skin bacterial infections such as acne and dermatitis.
Promote wound healing: It can provide a relatively sterile condition for the wound, and may promote cell proliferation and migration by regulating cytokines, thus accelerating wound healing and reducing scar formation.
Repair skin barrier: It can act on skin cells, regulate the expression of related proteins, promote the repair of damaged skin barrier function, thus enhancing the ability of skin to resist external causative agent.
Strengthen the immune system: Moderate regulation of the immune system, enhance the immune defence capacity, to help the body more effectively resist the invasion of causative agents.
Areas of application
Healthcare: Used in the development of new antibacterial drugs, wound dressings and skin repair products. For example, Fungi's medical repair dressing is mainly composed of antibacterial peptides, which are suitable for skin repair after medical surgery and for improving skin problems such as acne.
Food: Can be used as a natural preservative to inhibit the growth of microorganisms in food, thereby extending the shelf life of food.
Agricultural: It is used to prevent pests and diseases in plants and to enhance the resistance of plants to germs, and can also be used in animal farming to prevent infections in animals and reduce antibiotic use.
Advantage
Broad antibacterial profile: Compared with some traditional antibiotics, its antibacterial effect is more extensive, and it also has some effect on a variety of drug-resistant bacteria.
Low toxicity: The toxicity to human cells is low and the biosafety is good.
It’s not easy to develop resistance: Because its mechanism of action is different from that of traditional antibiotics, it is more difficult for microbes to develop a resistance to it.
At present, Antibacterial tridecapeptide-1 is still in the exploration stage of research and applications, and as research progresses, it is expected to play an important role in more fields.
Post time: 2025-07-31