Hexapeptide-11, a synthetic peptide widely used as an anti-aging ingredient in cosmetics, contains residues of alanine, phenylalanine, proline and valine. It can reduce the appearance of fine lines and wrinkles and is an excellent additive for various skin care and anti-aging products. Because it contains a unique group of amino acids, it is beneficial for regulating collagen levels and enhancing skin elasticity.
Scientists have discovered that people who have long been engaged in alcohol fermentation work have smoother, tighter and more tender skin than ordinary people. After long-term experiments, hexapeptide-11 was finally successfully isolated from the yeast fermentation liquid. Through research, it is precisely this polypeptide that gives the skin a magical effect.
Peptide-11 can enhance the expression of key genes for collagen production and important extracellular matrix components such as hyaluronic acid (HA) in dermal fibroblasts, promoting the generation of collagen and elastin, helping to firm the skin and maintain its integrity; increase the expression of antioxidant genes Nrf2, Keap1, NQO1 and TXNRD1 to prevent premature cellular aging caused by oxidative stress; and induce the activity of extracellular MMP-2 and MMP-9 enzymes, which is beneficial for wound repair. Therefore, Peptide-11 can be used for anti-aging purposes.
Post time: 2025-08-18