Oligopeptide-68, a polypeptide that can effectively inhibit melanin formation

Our skin color is influenced by the red protein in our blood vessels, the yellow carotenoids in our subcutaneous tissue, and the light pigment mechanism of melanin. Melanocytes are able to form melanin. The color of the skin is mainly affected by the content and distribution of this pigment. The epidermal layer of the skin can be divided into five layers, and the melanocytes are in the bottom basal layer. When the skin is stimulated (mainly by ultraviolet rays), the skin will stimulate the tyrosinase activity in the melanocytes to launch a self-defense, stimulate the conversion of tyrosine into dopa, and then produce more melanin in the basal layer to protect our skin.

In the process of melanin formation, tyrosinase plays a very important role. When tyrosinase activity increases, more melanin will be formed. If the activity of tyrosinase is controlled, the effect of melanocytes to form melanin is relatively reduced. There is no doubt that tyrosinase is the core of controlling melanin, so we can start by reducing the formation of tyrosinase and suppressing the activity of tyrosinase.

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Peptide-oligopeptide-68 that can effectively inhibit melanin formation

Oligopeptide-68 is a kind of whitening peptide raw material. It is an oligopeptide rich in 12 amino acids. It is usually used for whitening and brightening skin, eliminating spots and acne. It reduces melanin production and prevents excessive melanin formation by suppressing melaninotropic hormone. Its special principle is that oligopeptide-68 mimics the binding of TGF-β to cell surface receptors, and uses the repression of MITF intramolecular channels to reduce inducible and genetic pigmentation, so as to achieve the role of whitening and brightening. It reduces the number of molecules involved in melanin production and suppresses tyrosinase activity and melanin synthesis.


Post time: Feb-27-2024