pep2m vendor/243843-42-7/Peptide customization

Pep2m is a peptide inhibitor of the interaction between the C-terminal of the GluA2 (AMPA receptor) subunit and the N-ethylmaleimide sensitive fusion protein (NSF),(an opal that regulates AMPA receptor function). It is a linear peptide composed of 10 amino acids, which can reduce the postsynaptic current in CA1 neurons, the AMPA mediated current and the expression of AMPA receptor in cultured hippocampal neurons.

Specifications

Apperance: White to off-white powder

Purity(HPLC): ≥98.0%

Single Impurity: ≤2.0%

Acetate Content(HPLC): 5.0%～12.0%

Water Content (Karl Fischer): ≤10.0%

Peptide Content: ≥80.0%

Packing and Shipping: Low temperature, vacuum packing, accurate to mg as required.

FAQ：

How do you dissolve polypeptides?

The solubility of polypeptide depends mainly on its primary and secondary structure, the nature of modification label, solvent type and final concentration. If the peptide is insoluble in water, ultrasound can help dissolve it. For basic peptide, it is recommended to dissolve with 10% acetic acid; For acidic peptides, dissolution with 10%NH4HCO3 is recommended. Organic solvents can also be added to insoluble polypeptides. The peptide is dissolved in the least amount of organic solvent (e.g., DMSO, DMF, isopropyl alcohol, methanol, etc.). It is highly recommended that the peptide be dissolved in the organic solvent first and then slowly added to water or other buffer until the desired concentration.

How do I store peptides?
Usually the peptide product you receive is lyophilized powder packaging, please store the peptide in a dry, dark -20°C freezer immediately after receiving the sample to maintain the peptide stability as much as possible. Before use, place the polypeptide packaging tube from the freezer to a dry condition at room temperature, and allow the temperature to naturally warm to room temperature before opening the cap. Otherwise, water vapor in the air will enter the sample tube when the lid is opened, reducing peptide stability. Once opened, it should be weighed quickly and immediately sealed to avoid deliquescent, and hydrophilic peptides should be more careful to avoid repeated freezing and thawing. Outside temperature during short-term transportation will not affect the shelf life and quality of peptides.

What are peptides?

Peptides are short chain molecules formed by amino acids linked together by peptide bonds. They typically consist of 2 to 70 amino acids.

Are polypeptides harmful to humans?

Peptides, which are naturally present in the human body, are generally safe for use. However, some peptides may have specific pharmacological activities, and it is advisable to consult with a doctor or a professional before using them.

How To Order?

1. Contact us directly by phone or email: +86-13735575465, sales1@gotopbio.com.

2. Order online. Please fill out the order online form.

3. Provide peptide name, CAS No. or sequence, purity and modification if required, quantity, etc. we will provide a quotation within 2 hours.

4. Order conformation by duly signed sales contract and NDA(non disclosure agreement) or confidential agreement.

5. We will continuously update the order progress in time.

6. Peptide delivery by DHL, Fedex or others, and HPLC, MS, COA will be provided along with the cargo.

7. Refund policy will be followed if any discrepancy of our quality or service.

8. After-sale service: If our clients have any questions about our peptide during experiment, please feel free to contact us and we will respond to it in a short time.

All products of the company are only used for scientific research purpose, it’s prohibited to be directly used by any individuals on human body.